Archives: Month: June 2025

  • Could a Menopause Drug Help Prevent Invasive Breast Cancer? A New Study Offers Hope for DCIS Patients

    A recent Phase 2 clinical trial led by Northwestern Medicine suggests that Duavee, a medication already FDA-approved to treat menopause symptoms, might also help prevent invasive breast cancer in some women diagnosed with ductal carcinoma in situ (DCIS). The study, led by Dr. Swati Kulkarni, a breast surgeon and professor at Northwestern University Feinberg School of Medicine, was presented on June 1 at the American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago. What Was the Study About? The trial included 141 postmenopausal women with estrogen receptor-positive (ER+) DCIS, a type of early-stage breast condition that may sometimes lead to invasive cancer. Participants were randomly assigned…

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  • Listening to Patients, Changing Protocols: Dr. Melvin Silverstein’s Legacy in DCIS Care

    In this episode of the Cancer History Project podcast, Dr. Melvin Silverstein reflects on his groundbreaking work in breast cancer care—especially his role in changing how doctors treat and think about ductal carcinoma in situ (DCIS).  Interviewed by Dr. Stacy Wentworth, Silverstein shares stories from his decades-long career, including founding the Van Nuys Breast Center—the first free-standing breast center in the U.S.—and challenging widely accepted norms in cancer treatment. Silverstein is best known for developing tools like the Van Nuys Prognostic Index, which helped personalize DCIS treatment at a time when all patients were typically treated the same. He believed…

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