Category: Latest Research

New Study Maps Molecular Clues Behind Which DCIS Cases Progress to Invasive Breast Cancer

Due to improved screening, DCIS now makes up about one-quarter of all breast cancer diagnoses.  However, most cases of DCIS never progress to invasive breast cancer (IBC), meaning that many women undergo unnecessary aggressive treatments like surgery, radiation, and hormone therapy.  Molecular predictors of which DCIS cases will progress remain poorly understood. To better understand which DCIS cases are likely to progress to IBC, researchers studied nearly 200 breast tissue samples from DCIS patients who either stayed healthy or later developed invasive cancer. They analyzed the samples’ genes, DNA changes, and other molecular patterns.  The results were published earlier this month in Breast Cancer Research. The study concluded that DCIS…

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